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2016 POGO Symposium on Childhood Cancer

Posted on May 29, 2017 by Jamie Irvine


The 2016 POGO Symposium on Childhood Cancer – Leukemia: Successes, Advances, Challenges –examined clinical and scientific advances in the diagnosis and treatment of leukemia in children and adolescents and highlighted the impact of this disease on patients, parents and survivors.

Over 300 health professionals representing a variety of disciplines attended the conference, which sold out!

CLICK HERE TO VIEW THE PROGRAM

Click on the session titles below to view presentations that POGO has permission to share. 

NOTE: The content of each presentation below captures the unedited information and opinions presented by the speakers. Please note that the information contained in the presentations was current at the time it was presented – there may be further information in subsequent literature. Listed speaker credentials were current at the time of presentation.

The Long and Winding Road – A Brief History of Pediatric Leukemia
Stephen Sallan, MD

Managing Behavioural Changes During and After Treatment for Leukemia
Nina Kadan-Lottick, MD, MSPH

Quick Hits:
1. Immunizations – Marina Salvadori, MD, FRCPC
2. KiCS and PROFYLE: Precision Medicine Initiatives – David Malkin, MD, FRCPC
3. Minimal Residual Disease (MRD) Evaluation in Childhood ALL: A Health Policy Analysis – Nicole Bradley, MHSc

Implications of Treatment for ALL on Attention, Memory, and Learning
Sharon Guger, PhD

Asparaginase: The Good, the Bad and the Ugly
Paul Gibson, MD, FRCPC
Lee Dupuis, RPh., PhD
Stephen Sallan, MD 

Toxicity Management: Supportive Care Options for Children with Leukemia
Lillian Sung, MD 

Future Targets for Acute Myeloid Leukemia (AML)
Edward Anders Kolb, MD

Pain, Fatigue and Obesity: Managing Chronic Complications while on Therapy and Beyond
Ellen Lavoie Smith, PhD, APRN, AOCN, FAAN
Steven Mittelman, MD, PhD
Sue Zupanec, MN, NP-Pediatrics

Caring Beyond the Cure: Long-term Outcomes in Survivors of Childhood Leukemia
Paul Nathan, MD, MSc, FRCPC

The Future of Leukemia Therapy
Ching-Hon Pui, MD

Workshop A – Biology, Diagnosis and Treatment of Rare Leukemias
Jeff Lipton, PhD, MD, FRCPC
Mignon Loh, MD
Jim Whitlock, MD

Workshop B – Leukemia in the Down Syndrome Population
Kim S. Daniel, M.Ed, PhD
Johann Hitzler, MD
Jeffrey W. Taub, MD

Workshop C – Staying the Course: Addressing Compliance Challenges in the Treatment of Pediatric Leukemia
Wendy Landier, PhD, CRNP
Mark D. Minden, PhD, MD, FRCPC

Workshop D – Tiny Patients, Enormous Challenges: Treatment Approaches for Infant ALL
Patrick Brown, MD
Jennifer Drynan-Arsenault, BSc, BScPhm, RPh, ACPR
Krista Johnston, BScPT, MScPT(c) 

Posted in 2016 Symposium, Education for Health Professionals | Tagged acute lymphoblastic leukemia (ALL), AML, leukemia, Symposium 2016

The Long and Winding Road – A Brief History of Pediatric Leukemia

Posted on May 29, 2017 by Jamie Irvine


VIEW THE PRESENTATION

Speaker:
Stephen Sallan, MD
Chief of Staff, Emeritus Dana Farber Cancer Institute, Boston, MA

Dr. Stephen E. Sallan is Chief of Staff, Emeritus and the Quick Family Senior Investigator in Pediatric Oncology at Dana-Farber Cancer Institute, and a Professor of Pediatrics at Harvard Medical School. Dr. Sallan is one of the world’s foremost experts on childhood leukemia. His principal contributions include optimizing the use of asparaginase in acute lymphoblastic leukemia (ALL), enhancing outcomes in young adults with ALL, developing “therapeutic windows” for newly diagnosed patients, preventing therapy-related cardiotoxicity, and exploring innovative approaches to the prevention of chemotherapy-induced nausea and vomiting. After completing his education at Wayne State University in Detroit, he trained in pediatrics at Boston Floating Hospital, Children’s Hospital of Philadelphia, and the Hospital for Sick Children, Great Ormond Street, London. Since 1972, he has pursued his clinical and research career at Boston Children’s Hospital and the Dana Farber Cancer Institute.

Posted in 2016 Symposium | Tagged leukemia, Symposium 2016

Managing Behavioural Changes During Treatment for Leukemia

Posted on May 29, 2017 by Jamie Irvine

 


VIEW THE PRESENTATION

Speaker:
Nina Kadan-Lottick, MD, MSPH
Associate Professor of Pediatrics
Director of HEROS Survivorship Program
Leader Clinical Trial Program
Section of Pediatric Hematology-Oncology
Yale University School of Medicine, New Haven, CT

Dr. Kadan-Lottick, a pediatric hematologist-oncologist, is an Associate Professor at the Yale University School of Medicine and Director of the Yale HEROS Program for childhood cancer survivors. Dr. Kadan-Lottick’s research has concentrated on measuring and optimizing outcomes after treatment of childhood cancer, with an emphasis on leukemia. These studies have included cross-sectional and longitudinal studies of chemotherapy-induced cognitive changes, anxiety and depression, and family functioning during and after therapy. She was the principal investigator of two large multi-site longitudinal studies of quality of life outcomes and emotional functioning in children with acute lymphoblastic leukemia enrolled on front-line Children’s Oncology Group (COG) clinical trials. As a part of her focus on survivorship outcomes, Dr. Kadan-Lottick serves on the Children’s Oncology Group Survivorship Steering Committee, the Psychology Committee of the Childhood Cancer Survivorship Cohort Study, Consortium for New England Childhood Cancer Survivors Steering Committee, and the Board of Trustees for the Connecticut Chapter of the Leukemia and Lymphoma Society. She has also helped to author and revise the COG Long-Term Follow-up Guidelines.

Posted in 2016 Symposium | Tagged emotional health, leukemia, mental health, Symposium 2016

Quick Hits 2016

Posted on May 29, 2017 by Jamie Irvine


Immunizations 

VIEW THE QUICK HIT

Speaker:
Marina Salvadori, MD, FRCPC
Professor of Pediatrics
University of Western Ontario, London, ON
Pediatric Infectious Diseases Consultant
Children’s Hospital, London Health Sciences Centre , London, ON

Marina Salvadori graduated from medicine at Queen’s University in 1991. She did her residency training in pediatrics at the University of Manitoba, Winnipeg, then trained in infectious diseases at The Hospital For Sick Children in Toronto. She was working there in May 2000 and joined a team of pediatricians who responded to the call for help from Walkerton. She spent the summer of 2000 working in Walkerton, then moved to London in October 2000. She is currently an infectious diseases consultant at Children’s Hospital, London Health Sciences Centre and a Professor at the Schulich School of Medicine and Dentistry at the University of Western Ontario. She is the recipient of numerous teaching awards. She is very interested in vaccine preventable diseases, immunization education and advocacy. Dr. Salvadori is a member of the National Advisory Committee on Immunization, a past member of the Canadian Immunization and Infectious Diseases Committee.

KiCS and PROFYLE: Precision Medicine Initiatives

VIEW THE QUICK HIT

Speaker:
David Malkin, MD, FRCPC
Professor of Pediatrics and Medical Biophysics, University of Toronto
Staff Oncologist, Division of Hematology/Oncology
Senior Scientist, Genetics & Genomic Biology Program, Research Institute
The Hospital for Sick Children, Toronto, ON

Dr. Malkin is Professor of Pediatrics and Medical Biophysics, POGO Chair in Childhood Cancer Control, Faculty of Medicine, University of Toronto, and Medical Director of the Pediatric Oncology Group of Ontario. He is a pediatric oncologist, Director of the Cancer Genetics program, and a Senior Scientist in the Genetics and Genome Biology Program at SickKids. He is co-Director of the SickKids Cancer Sequencing (KiCS) program which integrates and translates next generation sequencing into clinical care of children with cancer, and Director of the national multi-institutional TFRI Precision Oncology For Young People (PROFYLE) initiative which is establishing a pipeline for incorporation of next generation sequencing and variant modeling to incorporation of novel clinical trials for children and young adults with hard to treat cancers across Canada. Dr. Malkin’s research program focuses on: 1) genetic and genomic mechanisms of childhood cancer susceptibility; and 2) signaling pathways and novel therapeutic targets in rhabdomyosarcoma. Recently, his work has addressed the application of genomics to develop rational clinical surveillance and treatment guidelines for children and adults at genetic ‘high risk’ for cancer. His work has been funded by TFRI, Canadian Cancer Society, CIHR, CFI, Genome Canada, the NIH, Ewing Foundation Canada, and the Department of Defense (US).

Minimal Residual Disease (MRD) Evaluation in Childhood ALL: A Health Policy Analysis

VIEW THE QUICK HIT

Speaker:
Nicole Bradley, MHSc
Senior Healthcare Analyst & Project Manager
Pediatric Oncology Group of Ontario (POGO)

Nicole Bradley has a Masters of Health Science (MHSc) degree in Community Health & Epidemiology from the University of Toronto. Nicole has been involved in a variety of research studies and applied analyses related to epidemiology, health services research, policy development and quality of life in pediatric and adult oncology – with 18 peer-reviewed publications and over 30 oral and poster presentations based on this work. Nicole has been awarded with numerous recognitions for her work as a young investigator, including recognition for one of the “top ten Canadian Cancer Society funded research studies of 2010.” Since 2009, Nicole has been involved with policy and program development with POGO. She is particularly interested in the use of evidence to support policy and program development and health system design to improve the quality of the healthcare system.

Posted in 2016 Symposium | Tagged leukemia, Symposium 2016

Implications of Treatment for ALL on Attention, Memory, and Learning

Posted on May 29, 2017 by Jamie Irvine


VIEW THE PRESENTATION

Speaker:
Sharon Guger, PhD
Pediatric Neuropsychologist, AfterCare Program
The Hospital for Sick Children, Toronto, ON

Dr. Sharon Guger received her PhD in clinical-developmental psychology at York University in 2000 and then completed a post-doctoral fellowship in pediatric neuropsychology at The Hospital for Sick Children (SickKids) with Dr. Brenda Spiegler. Her 16 years of experience as a neuropsychologist have included clinical practice, research, and teaching.

Dr. Guger is a pediatric neuropsychologist with the AfterCare Program in the Division of Haematology/ Oncology where she provides neuropsychology assessment and consultation services primarily to children, teens and transition-aged young adults with a history of leukemia/lymphoma or brain tumours. As well, she is involved in efforts at promoting transition to adult healthcare at both individual and systemic levels. Dr. Guger’s research has focused on developing a better understanding of the long-term outcomes of children and youth with leukemia and brain tumours. Specifically, she is interested in individual and contextual variables that influence disease and treatment-related neurocognitive and psycho-social deficits with the goal of identifying those at greatest risk in order to implement targeted interventions and promote optimal outcome. Dr. Guger is also the Director of Clinical Psychology Training in the Department of Psychology, responsible for practicum, pre-doctoral internship and post-doctoral fellowship.

Posted in 2016 Symposium | Tagged acute lymphoblastic leukemia (ALL), leukemia, Symposium 2016

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