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2018 POGO Pre-Symposium Nursing Seminar

Posted on November 22, 2018 by Jamie Irvine


On November 1, 2018 POGO hosted a one-day nursing seminar the day before the 2018 Multi-Disciplinary Symposium on Childhood Cancer. Topics covered included: Practical strategies to improve Patient/Family Education; CAR-T and other Immunotherapies; Survivorship in the Age of Precision Medicine; and Strategies to Maintain Optimism and Build Resilience for Pediatric Oncology Nurses. 

Over 90 nurses and other health care professionals from across Ontario and beyond attended the conference.

VIEW THE PROGRAM

PLENARY SESSIONS

Closing the Gap, Bridging the Divide: How to Effectively Teach Patients and Families
Stephanie Cox, RN(EC), MN, NP-Pediatrics
Angela Filice, RN

Avoiding Information Overload: What do Families Actually Need to Know?
Jen Sullivan, MSN, RN, CPON

Managing Stress and Cultivating Optimism: Enhancing Resiliency in Pediatric Oncology Nurses
Teresa Conte, PhD, CPNP

QUICK-HIT SESSIONS

Management of Fatigue in Children and Adolescents with Cancer and Pediatric Recipients of Hematopoietic Stem Cell Transplants: A Clinical Practice Guideline
Lillian Sung, MD, PhD

CAR-T Cell Therapy: Patient Eligibility, Management, and Nursing Considerations
Colleen Callahan, RN, MSN, CRNP

Stopping Cancer Cell Evasion with Immune Therapies
Sue Zupanec, MN, NP Pediatrics

New Therapies, New Late Effects – Survivorship in the Age of Precision Medicine
Eleanor Hendershot, RN(EC), MN, BScN, NP Pediatrics

BRAF Inhibition and Fusion in Low Grade Glioma
Tara McKeown, MN NP Pediatrics

Posted in 2018 Pre-Symposium Nursing Seminar, Education for Health Professionals | Tagged 2018 symposium, CAR-T, fatigue, immune, new therapies, Nurses, stress

CAR-T Cell Therapy: Patient Eligibility, Management, and Nursing Considerations

Posted on November 22, 2018 by Jamie Irvine


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Presentation Description:
Pediatric acute lymphoblastic leukemia (ALL) is the most common childhood cancer. There have been significant improvements in pediatric ALL survival rates over the past 50-60 years. Unfortunately, approximately 15% of patients relapse and cure rates are much lower after relapse. Many of these patients require newer, more novel therapies and targeted immunotherapy using anti-CD19 chimeric antigen receptor T cells (CAR T) is one of those therapies. A patient’s own T cells are collected and then genetically engineered to recognize and attack CD19 + tumors. Benefits of CAR T cell therapy include expansion of the CAR T cells in the patient and potential for long-term persistence for disease surveillance. This therapy has shown encouraging results in patients with refractory and relapsed ALL. With therapies like this becoming more widely available, pediatric oncology nurses will need to understand the concept of these therapies and know the risks and side effects in order to provide care to these patients. Nurses play an important role in providing safe care and patient management. They are often the first clinicians to recognize side effects and problems. There is also a significant role for nurses in providing anticipatory guidance and education for patients and their families.

Speaker:
Colleen Callahan
, RN, MSN, CRNP
Nurse Practitioner, Division of Oncology
Children’s Hospital of Philadelphia

Colleen Callahan, MSN, CRNP, has worked in pediatric oncology for 23 years, 18 of which as a nurse practitioner in the Oncology Division at Children’s Hospital of Philadelphia. She has worked in the Cancer Immunotherapy Program for the past five years caring for patients pre, during, and post CAR T-cell therapy in the outpatient setting. She follows these patients from their initial referral to the cancer immunotherapy team, through their T cell collection, T cell infusion, and then after infusion monitoring for side effects, adverse events, and long-term effects and responses.

Posted in 2018 Pre-Symposium Nursing Seminar | Tagged 2018 pre-symposium, CAR-T, nursing

2018 POGO Symposium on Childhood Cancer

Posted on November 22, 2018 by Jamie Irvine


The 2018 POGO Multi-Disciplinary Symposium on Childhood Cancer – Precision Medicine in Pediatric Oncology – examined clinical and scientific advances in precision medicine and explored how those advances are impacting the diagnosis and treatment of cancer in children.

Over 250 delegates representing a variety of disciplines attended the conference.

VIEW THE PROGRAM

Click on the session titles below to view presentations that POGO has permission to share. 

PLENARY SESSIONS

Precision Medicine in the Pediatric Oncology Clinic: From Feasibility to Clinical Impact
Katherine Janeway, MDMD, MMSc

Precision Medicine – A Paradigm Shift?
Ian F. Tannock, CM, MD, PhD, DSc
Uri Tabori, MD

Thinking Practically: Delivery of Care Considerations for New Agents
Karen Fung, MSW, RSW
Tara McKeown, RN MN NP-Paediatrics

Ethics and Consent in the Age of Precision Medicine – Forging a Path Forward
Steven Joffe, MD, MPH

Select Poster Presentations
Alexandra Zorzi, MD, FRCPC
Andrew Shuen, PhD Candidate, MD, FRCPC
Lauren Mulrooney
, Nursing Student (3rd year)
Valli Subasri, MSc candidate (Medical Biophysics)
Nicole Espinosa, BScH Candidate (Life Sciences)
Mohammad R. Alqudimat, PhD Student (Nursing)
Marta Wilejto, Assistant Professor Paediatric Hematology/Oncology
Sarah Naraine, Fourth Year Nursing Student
Ceilidh Eaton Russell, PhD
Jill Furzer, PhD candidate (health economics)

Targeted and Traditional Agents: Can We Reduce Side Effects Using Pharmacogenomic and Endogenous Biomarkers?
Richard B. Kim, MD, FRCPC

The Future of Immunotherapy, CAR-T and Beyond
Shannon L. Maude, MD, PhD

WORKSHOPS

The Evolution of Clinical Trials in Canada
Rebecca Deyell, MD, MSc, FRCPC
Josh Silvertown, PhD, MBA, MSM
Patrick Sullivan

PROFYLE/KiCS: The ABCs of Precision Medicine in Canada
Alexandra Zorzi, MD
Anita Villani, MD, MSc, FRCPC
Andrea Cote, RN, BScN

CAR-T Cell Therapy in Ontario: Opportunities and Challenges
Joerg Krueger, MD
Stacey Marjerrison, MD, MSc, FRCPC
Colleen Callahan, RN, MSN, CRN

Posted in 2018 Symposium, Education for Health Professionals | Tagged 2018 symposium, CAR-T, Clinical Trials, consent, diagnos, ethics, genetics, pharmacology, precision therapy, psychosocial, side effects

The Future of Immunotherapy, CAR-T and Beyond

Posted on November 22, 2018 by Jamie Irvine


VIEW THE PRESENTATION

Speaker:
Shannon L. Maude,
MD, PhD
Assistant Professor of Pediatrics, Divison of Oncology
Children’s Hospital of Philadelphia, University of Pennsylvania School of Medicine

Dr. Shannon Maude is an oncologist in the Cancer Immunotherapy Program at Children’s Hospital of Philadelphia and an Assistant Professor of Pediatrics at the University of Pennsylvania Perelman School of Medicine. After earning her undergraduate degree in biology from the University of Virginia, Dr. Maude received her MD and PhD from the University of Pennsylvania School of Medicine, and completed her residency in pediatrics as well as a fellowship in pediatric hematology-oncology at Children’s Hospital of Philadelphia. Dr. Maude is Fellowship Director of the Cancer Immunotherapy and BMT Fellowship at Children’s Hospital of Philadelphia and a Medical Director in the Center for Cellular Immunotherapies at the University of Pennsylvania. She leads clinical trials of engineered T cell therapies for childhood cancers. Dr. Maude has a special interest in novel therapies for acute lymphoblastic leukemia, particularly targeted therapy approaches and engineered T cell therapy.

Posted in 2018 Symposium | Tagged 2018 symposium, CAR-T, immunotherapies

CAR-T Cell Therapy in Ontario: Opportunities and Challenges

Posted on November 22, 2018 by Jamie Irvine


VIEW THE PRESENTATION*

*Joerg Krueger’s and Stacey Marjerrison’s presentation slides not included 

Presentation Description:
Chimeric antigen receptor T cell therapy (CAR T) has shown encouraging results in patients with refractory and relapsed ALL and will soon be available in Ontario. This workshop will: 1) Examine the current state of CAR-T cell trial access in Ontario; 2) Provide an overview of the CAR-T cell program at the Hospital for Sick Children, which is set to be operational in late 2018; 3) Discuss the out of country review process for patients who do not qualify for the CAR-T cell therapy trial at the Hospital for Sick Children; and 4) explain the intake process and experience of patients and families who travel to Children’s Hospital of Philadelphia for this treatment.

Speakers:
Joerg Krueger
, MD (slides unavailable)
Staff Physician, Department of Haematology/Oncology
The Hospital for Sick Children
Assistant Professor
University of Toronto
Project Investigator
Research Institute

Dr. Krueger obtained his medical degree from Humboldt University, Berlin, Germany. He completed his doctoral thesis at Humboldt and a post-doctoral fellowship at the Scripps Research Institute, La Jolla, California, with a research focus on cancer immunotherapies.

After finishing his pediatric residency at the Charité University Hospital, Berlin, he did a fellowship in the Department of Hematology and Oncology at The Hospital for Sick Children, Toronto. He was recruited as full-time staff to The Hospital for Sick Children and Assistant Professor at the University of Toronto in 2015 and is part of the Hematopoietic Stem Cell Transplantation and Cellular Therapy/Apheresis team.

Colleen Callahan, RN, MSN, CRNP
Nurse Practitioner, Division Of Oncology
Children’s Hospital of Philadelphia

Colleen Callahan, MSN, CRNP, has worked in pediatric oncology for 23 years, 18 of which as a nurse practitioner in the Oncology Division at Children’s Hospital of Philadelphia. She has worked in the Cancer Immunotherapy Program for the past five years caring for patients pre, during, and post CAR T-cell therapy in the outpatient setting. She follows these patients from their initial referral to the cancer immunotherapy team, through their T cell collection, T cell infusion, and then after infusion monitoring for side effects, adverse events, and long-term effects and responses.

Stacey Marjerrison, MD, MSc, FRCPC (slides unavailable)
Pediatric Hematologist/Oncologist
AfterCare Program Medical Director
McMaster Children’s Hospital
Assistant Professor of Pediatrics
McMaster University

Dr. Stacey Marjerrison is a pediatric oncologist and the Director of the AfterCare Program at McMaster Children’s Hospital. Dr. Marjerrison’s areas of interest are in supportive care for children with cancer and in the interaction between socio-demographic determinants of health and malignancy. Broadly, her work focuses on provision of care for marginalized populations, including Indigenous children in Canada and for all children in low-income countries. As applied to survivors of childhood cancer, this includes building care programs that encourage survivors to engage in healthy active lifestyles.

Dr. Marjerrison is an inaugural member of the Adoptive T-cell Immunotherapy Review Panel of the Ministry of Health and Long-term Care of Ontario and Cancer Care Ontario.

Posted in 2018 Symposium | Tagged 2018 symposium, CAR-T

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