Presentation Description: Certain chemotherapy drugs such as anthracyclines and/or radiation in the heart region, have greatly improved survival of childhood cancer, but can have late effects on heart function. Dr. Ross Davies, an adult Cardiologist at the University of Ottawa Heart Institute, has experience with heart failure and heart transplantation, including some patients who have been survivors of childhood cancer. In this presentation, he discussed the effects of chemotherapy and radiation on the heart, non-invasive cardiac diagnostic tests used to assess heart function such as echocardiography or radionuclide ventriculography, cardiac medications which can be given to improve heart function and heart healthy behavior including diet and exercise advice for survivors of pediatric cancer. He also explored some of the relevant publications such as the Children’s Cancer Survivor Study.
Speaker: Â Â Â Â Â Â Â Â Ross Davies, BSc, MD, FRCPC, FACC
                         Professor of Medicine, University of Ottawa
                          Member, Heart Failure, Transplant and Pulmonary Hypertension Programs
                          Division of Cardiology
                          University of Ottawa Heart Institute
Presentation Description:Â Survivors of childhood cancer are at increased risk of developing chronic medical conditions, primarily as a direct result of the treatments they received to cure their cancers (for example radiation, combination chemotherapy). Endocrine or hormone problems are among the most common chronic medical conditions seen in adult survivors of childhood cancer. Hormone problems are most often seen in persons who were treated with radiation to the brain, neck or pelvic area and those who received high doses of a class of chemotherapy drugs called alkylation agents (such as cyclophosphamide, busulfan, melphalan, thiotepa). Hormone problems can affect growth, sexual development, stamina, and overall well being. Fortunately, many hormone problems are treatable.
This presentation reviewed the major hormone complications seen in survivors of childhood cancer, risk factors for these problems, as well as common symptoms and treatment approaches.
Speaker: Â Â Â Â Â Â Â Â Mark Greenberg
                         Senior Adviser, Policy & Clinical Affiars
                          Pediatric Oncology Group of Ontario (POGO), Toronto
                          Senior Staff Oncologist
                        Division of Haematology/Oncology, SickKids, Toronto
                        Professor of Paediatrics & Surgery, University of Toronto
