Workshop D – Tiny Patients, Enormous Challenges: Treatment Approaches for Infant ALL


Workshop Description:
A diagnosis of acute lymphoblastic leukemia (ALL) in infancy is rare, and poses serious challenges for health providers and families alike. This workshop will examine the biology and diverse therapeutic approaches to the treatment of infant ALL; discuss pharmacological considerations for this patient group; and present a brief overview of how the “Beanstalk Program” is used to prevent delay in neurodevelopment and how this compliments rehabilitation in haematology/oncology and bone marrow transplant.

Patrick Brown, MD
Director, Childhood Leukemia Program
Johns Hopkins University, Baltimore, MD
Sidney Kimmel Cancer Center, Baltimore, MD

Dr. Pat Brown received his medical degree from the Medical University of South Carolina, in Charleston. He subsequently completed an internship and residency in pediatrics at Johns Hopkins, and went on to a three-year joint clinical fellowship with Johns Hopkins and the National Cancer Institute in pediatric hematology-oncology.

Dr. Brown is a member of the American Society of Hematology, the American Association for Cancer Research, and the American Society of Pediatric Hematology/Oncology. He is vice-chair for relapse and an executive steering committee member of the Acute Lymphoblastic Leukemia (ALL) Committee in the Children’s Oncology Group, and he co-chairs the National Comprehensive Cancer Network’s Clinical Guidelines Panel for ALL. He has been published in over 50 peer-reviewed journal articles and book chapters.

His research focuses on developing new therapies for childhood leukemia—specifically, leukemias with very low cure rates. His laboratory is working to develop new treatments that can overcome resistance to chemotherapy and that, unlike chemotherapy, selectively target leukemia-causing mutations. He is a principal investigator on several clinical trials testing promising combinations of standard chemotherapy with novel targeted drugs.

Jennifer Drynan-Arsenault, BSc, BScPhm, RPh, ACPR
Clinical Pharmacist, Division of Haematology/Oncology and Bone Marrow Transplantation
The Hospital for Sick Children, Toronto, ON

Jennifer attended Queen’s University where she studied biology prior to completing a pharmacy degree at the University of Toronto. She completed her pharmacy residency at Sunnybrook Hospital and Women’s College Hospital. After practicing in adult oncology at Mount Sinai Hospital, she moved to The Hospital for Sick Children where she works in both the inpatient and outpatient setting within the Division of Haematology/Oncology and Bone Marrow Transplantation.

Krista Johnston, BScPT, MScPT(c)
The Hospital for Sick Children, Toronto, ON

Krista Johnston is a full-time physiotherapist in the areas of haematology/oncology and bone marrow transplant. She provides inpatient assessment and treatment as well as outpatient consultation and has been part of the Neuroscience team at SickKids since 2007.

Krista has a status appointment with the University of Toronto and has active involvement in lecturing for the physiotherapy curriculum and is a preceptor for students. Krista has been a part of many hospital initiatives involving safe sleep and falls prevention in addition to initiatives to promote mobility and neurodevelopment. Krista has been involved in research with the brain tumour population and multi-centre research projects involving children with leukemia. She has just completed her own research looking at how children with cancer are mobilizing when admitted to hospital.

*Patrick Brown presentation slides not included

Comments are closed.