Presentation Description: When a child is treated for cancer, the number of malignant cells exposed to chemotherapy and radiation is a tiny fraction of the normal cells also exposed. This unwanted exposure of normal tissues to the damaging effects of treatment is the cause of a wide array of acute and late toxicity, including infertility, cognitive impairment, and second malignancy.
This presentation described strategies to minimize the exposure of normal tissues to toxic exposures, principally radiation therapy but also chemotherapy, by advances in imaging, radiation delivery, and targeted therapeutics.
David Hodgson, MD, MPH, FRCPC
Princess Margaret Hospital, Toronto