POGO was not granted permission to post this presentation. We apologize for the inconvenience.
Blog
Tag: stem cell
Brain Cancer Stem Cells – the Evolving Story
POGO was not granted permission to post this presentation. We apologize for the inconvenience.
Cutting the Roots: Can we Cure Sarcomas by Understanding Stem Cells?
Presentation Description: A small portion of stem cells in a given tissue give rise to all of the cells that make up that tissue, and help regenerate and maintain the tissue over its lifespan. Cells with these characteristics have been identified in a variety of tumor types and are called tumor initiating cells (TIC). A subpopulation of cells with TIC characteristics have been identified in a number of sarcomas, along with some novel characteristics within this TIC population. Some of these characteristics can be exploited using novel chemotherapeutic approaches. At the time of the presentation, these approaches were being tested in mouse models of sarcomas.
Speaker:
Benjamin Alman, MD, FRCSC
Head, Division of Orthopaedic Surgery
Senior Scientist, Program in Developmental & Stem Cell Biology
The Hospital for Sick Children, Toronto, ON
2011 POGO Symposium on Childhood Cancer
The 2011 POGO Multi-Disciplinary Symposium on Childhood Cancer – Unraveling the Mysteries of Transplantation – examined clinical and scientific advances in pediatric stem cell transplantation as treatment for various types of cancers. It focused on the medical and psychosocial impacts of this intensive intervention on patients, families, donors and survivors, and examined important ethical issues. A multi-disciplinary audience of over 270 healthcare professionals attended. Learning objectives included:
- Recognize and examine critical milestones in the evolution of pediatric stem cell transplantation.
- Identify and manage clinical complications affecting pediatric stem cell transplant patients.
- Recognize and mitigate psychosocial effects of transplant on patients, families, donors and survivors.
- Identify and evaluate ethical issues relating to pediatric stem cell transplantation.
- Demonstrate improved communication skills to promote co-operative integrated management of pediatric stem cell transplant patients.
VIEW THE PROGRAM
NOTE: The content of each presentation below captures the unedited information and opinions presented by the speakers. Please note that the information contained in the presentations was current at the time it was presented – there may be further information in subsequent literature. Listed speaker credentials were current at the time of presentation.
The Evolution of Pediatric Stem Cell Transplantation
Presentation Description: The field of haematopoietic stem cell transplantation (SCT) had its firm beginnings in paediatrcis with the first successful bone marrow transplant being performed in 1968 on a child with severe combined immune deficiency. Today more than 15,000 allogeneneic SCTs are performed worldwide with around one quarter of those occurring in children suffering from a wide variety of malignant and genetic disorders. There is no doubt that SCT represents one of the most innovative treatments of the last decades, and while the principles of SCT have remained the same, dramatic changes in the details of SCT over the last forty years have led to significant improvements in the outcome. While many children are now cured from otherwise fatal disorders, much work is still required to reduce both acute toxicities, and specifically in children, the long-term side effects of these procedures.
Speaker:
Paul Veys, MBBS, FRCP, FRCPath, FRCPH
Director, Blood and Marrow Transplantation
Great Ormond Street Hospital for Children, London, England
Reader in Stem Cell Transplantation
UCL Institute of Child Health Molecular Immunology Unit