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Tag: drug therapies


Pharmacological and Nonpharmacological Interventions for Cognitive Late Effects

Posted on November 6, 2015 by admin


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Presentation Description: 
Survivors of CNS impacting cancers diagnosed in childhood are at significant risk for cognitive impairments. As survival rates improve, efforts to optimize cognitive outcomes take on added importance. Historically, there have been few empirically supported interventions for cancer survivors. Findings from pharmacologic interventions, largely using methylphenidate, have revealed an intervention that is safe and efficacious. However, there remain children for whom stimulant medications are not a viable option due to medical contraindication, parental preference or poor medication response.

Findings from nonpharmacologic, therapist-delivered interventions offer initial encouragement, particularly for improving academic skills; yet, time and financial requirements are high for relatively modest benefits, and individuals must reside in close proximity to providers. Computerized cognitive training offers added advantages of remote administration, decreased personnel resources and standardized implementation. Studies have demonstrated the feasibility, acceptability and efficacy of this approach, with neuroimaging findings suggestive of training-related neuroplasticity. Generalization of benefits to non-trained skills and maintenance of benefits over time are being investigated. Future directions include the use of genetics and neuroimaging to identify cognitive risk early in treatment as well as individualize intervention approaches.

This presentation provided an overview of pharmacologic and nonpharmacologic interventions for cognitive late effects experienced by childhood cancer survivors, including novel interventions currently under investigation.

Speaker:
Heather M. Conklin, PhD
Chief, Neuropsychology Section
Associate Member, Department of Psychology
St. Jude Children’s Research Hospital, Memphis, TN

 

Posted in 2015 Pre-Symposium Psychosocial Seminar, Misc, Pre-Symposium Seminars | Tagged 2015 Pre-Symposium Psychosocial Seminar, cognitive, drug therapies, interventions, late effects

A Fine Balance: The Economics of Drug Therapy

Posted on November 6, 2015 by admin


VIEW THE PRESENTATION

Presentation Description: 
This panel discussion discussed approaches to securing funding for new drug therapies used for relapsed disease and the decision-making process around the development and dissemination of these novel drug therapies.  The panel presentation involved three different perspectives on cost and resource implications from a provincial, medical economics and hospital administration perspective. 

Speakers:
Jaclyn Beca, MSc
Manager, Pharmaeconomics Research Unit
Cancer Care Ontario, Toronto

Suzanne McGurn, RN, BScN, MPA
Assistant Deputy Minister and Executive Officer
Ontario Public Drug Programs

Judy Van Clieaf, RN, BScN, MN
Vice-President, Clinical
The Hospital for Sick Children

Note: POGO was not granted permission to share Jaclyn Beca’s or Judy Van Clieaf’s slides.

Posted in 2015 Symposium | Tagged 2015 Symposium, drug therapies, funding, pharmaeconomics, relapse

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