2.2.2 Children Not Eligible for Chemotherapy Administration in a Satellite Centre
Eligibility for Chemotherapy Administration in a Satellite Centre is constrained by:
- Children of any age whose disease demands high intensity, ongoing, rapidly progressing inpatient chemotherapy. Exceptions are as follows:
- Where the protocol specified therapy, at any time, falls within the individual agent guidelines, ( e.g. vincristine administration) or is deemed no more toxic than agents already specified as acceptable;
- As new chemotherapy agents become available and are used on protocol, their toxicities and their appropriateness for use in the satellite context will have to be evaluated; new agents may then be added, as appropriate, to the Table of Antineoplastic Agents approved for administration in the satellite context and suitable knowledge transfer undertaken;
- Administration of chemotherapy agents to patients with end stage disease (e.g. neuroblastoma, relapsed AML) which are palliative to ease the burden of care for families.
- Children who have experienced significant, immediate toxicity with a given chemotherapeutic agent, e.g. anaphylactic reaction, seizures, cerebral edema.
- Children who have undergone HPSCT transplant until specifically approved by the transplant center