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Research & Data

POGO > Research & Data > POGO Research Unit > Research Funding > Past Seed Grant Recipients
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Past Seed Grant Recipients

POGO’s 2019 Seed Grant Recipients

Alisha Kassam, MD, MPH, FRCPC and Sumit Gupta, MD, PhD, FRCPC
Lillian Sung, MD, PhD
Jennifer Stinson, RN-EC, PhD, CPNP & Mohammed Alquidimat


Alisha Kassam, MD, MPH, FRCPC and Sumit Gupta, MD, PhD, FRCPC

Project Title: Understanding End-of-Life Health Care Utilization in Adolescents and Young Adults with Advanced Cancer

Principal Investigator: Alisha Kassam, MD, MPH, FRCPC and Sumit Gupta, MD, PhD, FRCPC

Co-Investigators: Abha Gupta, MD, MSc, FRCPC, Adam Rapoport, MD, MHSc, FRCPC, Amirrtha Srikanthan, MD, MHSc, FRCPC, CHE, Craig Earle, MD MSc FRCP(C), Kimberley Widger, RN, PhD, CHPCN(C), Rinku Sutradhar, PhD

Project Summary: The investigators hope to provide baseline data on the intensity of end-of-life care being delivered specifically to adolescents and young adults in Ontario.

Impact/Relevance: Data from this study will help identify vulnerable populations, inform clinicians and policy makers, and suggest future research interventions to improve the quality of palliative and end-of-life care delivered to adolescents and young adults with cancer.

Funding: $14,986.00


Lillian Sung, MD, PhD

Project Title: Development and Validation of Proxy-report Symptom Screening in Pediatrics Tool (SSPedi) and Self-report mini-SSPedi in Children Younger than Eight Years.

Principal Investigator: Lillian Sung, MD, PhD

Co-Investigators: Deborah Tomlinson, RN, MN, L. Lee Dupuis, RPh, PhD, Paul Gibson, MD, FRCPC, Donna Johnston, MD, FRCPC

Project Summary: This project focuses on validating a symptom screening instrument for children receiving cancer treatments who are aged 2 to 7 years.

Impact/Relevance: Most children with cancer will experience severe and distressing treatment-related symptoms. This research is a first step toward improving symptom control in younger children with cancer by enabling them to communicate bothersome symptoms to family members and providers.

Funding: $14,980.00


Jennifer Stinson, RN-EC, PhD, CPNP & Mohammed Alquidimat, PhD Student (Nursing)

Project Title: Validating a Questionnaire to Assess the Use of Complementary Health Approaches Among Children with Cancer and Their Parents

Principal Investigator: Jennifer Stinson, RN-EC, PhD, CPNP

Co-Investigators: Mohammad Alqudimat, PhD Student (Nursing), Karine Toupin April, PhD, Lindsy Jibb, RN, PhD, Paul Nathan, MD, MSc, FRCPC, Charles Victor, MSc

Project Summary: Using a phased approach, the investigators will conduct electronic surveys with experts to determine how to modify the items of the existing questionnaire. Youth with cancer, parents of youth with cancer, and cancer healthcare providers will then take part in individual interviews to determine what changes should be made. The questionnaire will be modified based on the results of each round of interviews.

Impact/Relevance: The proposed study will provide an instrument that will enable healthcare providers to initiate clinical discussions about the benefits and potential harms of complementary health approaches (CHA). Routine use of this instrument may help healthcare providers and researchers to determine what approaches are being used and which may be helpful, thus leading to the development of a new CHA research agenda for pediatric oncology.

Funding: $ 14,999.00


POGO’s 2018 Seed Grant Recipients

Eric Bouffet, MD, FRCPC
Denise Mills, MN, NP Pediatrics
Lindsay Jibb, RN, PhD


Eric Bouffet, MD, FRCPC

Project Title: Parent-Child Communication When a Child Has a Life-Threatening Illness

Principal Investigator: Eric Bouffet, MD, FRCPC

Co-Investigators: Adam Rapoport, MD, MHSc, FRCPC; Ceilidh Eaton Russell, PhD(c), CCLS

Project Summary: The investigators wish to interview parents and children in order to learn how they talk together about the child’s illness, its impacts on their lives, their feelings and worries, including any about the future or death.

Impact/Relevance: Helping children and parents share their thoughts and feelings, and support each other, can strengthen their relationships and improve quality of life. This project will teach caregivers how to support children’s and parents’ coping, well-being and quality of life during and after therapy no matter what the prognosis, potentially helping every family touched by childhood cancer.

Funding: $14,991.20


Denise Mills, MN, NP Pediatrics

Project Title: Improving Quality and Consistency in Family Education Prior to First Discharge Following a Pediatric Cancer Diagnosis

Principal Investigator: Denise Mills, MN, NP Pediatrics

Co-Principal Investigator: Sue Zupanec, MN, NP Pediatrics

Collaborators: Angela Punnett, MD; Vicky Breakey, MD; Paul Gibson, MD; Lillian Sung, MD

Project Summary: In this study, investigators want to ask parents if they like and can easily learn information about how to care for their child with cancer from short videos that highlight key points, have visual cues, and provide case examples. If parents find short videos useful and helpful for learning, investigators hope they will feel more confident to care for their child and have lower levels of anxiety.

Impact/Relevance: Investigators are proposing a novel video-based education program for parents and caregivers, which they hypothesize will lead to improved understanding and confidence to care for children newly diagnosed with cancer, after the first discharge from hospital. The greatest impact will be on the parents and caregivers with a goal to increase knowledge, preparedness and confidence, while minimizing distress and anxiety.

Funding: $14,995.75


Lindsay Jibb, RN, PhD

Project Title: Needs Assessment Focused on Home-Based Care for Children with Cancer: A Qualitative Descriptive Study Using the Perspectives of Children, Parents and Healthcare Providers

Principal Investigator: Lindsay Jibb, RN, PhD

Co-Investigators: Donna Johnston, MD; Julie Chartrand, RN, PHD

Project Summary: Children with cancer, their parents and their healthcare providers will be interviewed to find out what they think about receiving some of their cancer care at home and any needs they have related to home-based care. Thus far, research has shown that receiving care for cancer can be tough for children and their families. Increasingly, some cancer care is being delivered to children in their homes, but little is still known about what children, parents and healthcare providers think about children getting cancer care at home and how research can make this care better.

Impact/Relevance: Once investigators complete the study and more is known on these topics, they will be able to decide on what research to do to provide the best possible home care to children with cancer. Investigators hope that by providing high-quality home-based care to children with cancer, there will be an improved quality of life for the children, as well as for their families.

Funding: $14,986.33


POGO’s 2017 Seed Grant Recipients

Anne Klassen, DPhil (Oxon)
Brian Timmons, PhD and Vicky Breakey, MD, FRCPC, MEd
Petros Pechlivanoglou, PhD


Anne Klassen, DPhil (Oxon)

Project Title: Establishing Content Validity of FACE-Q Kids for Pediatric Head and Neck Cancer

Principal Investigator: Anne Klassen, DPhil (Oxon)

Co-Investigators: Dr. David Dix, Dr. Paul Nathan, Dr. Eric Bouffett

Project Summary: Patient-reported outcome instruments (PROs) are questionnaires that measure outcomes (eg, quality of life) that matter to patients by asking them directly. The study
aims to determine if a new PRO called FACE-Q Kids can be used in head/neck (HN) cancer.

Impact/Relevance: A facial difference can have an important impact on a person’s QOL.
In order to measure outcomes in pediatric HN cancer, carefully conceptualized, valid, reliable,
and responsive PROs are needed. Given that appearance and facial function are concepts not well addressed in current cancer PROs, it is anticipated that the FACE-Q Kids-oncology module will be
widely adopted in HN cancer treatment studies and clinical practice.

Funding: $14,998


Brian Timmons, PhD and Vicky Breakey, MD, FRCPC, MEd

Project Title: Using Exercise to Boost the Immune System of Children with Acute Lymphoblastic Leukemia

Principal Investigator: Brian Timmons, PhD and Vicky Breakey, MD, FRCPC, MEd

Co-Investigators: Dr. Adam Fleming, Dr. Stacey Marjerrison, Dr. Joyce Obeid, Dr. Lehana Thabane

Project Summary: Acute lymphoblastic leukemia (ALL) is the most common type of childhood cancer. Treatment for ALL lasts 2-3 years and results in a weakened immune system, putting kids at risk for infection. The combination of inactivity and the side effects of chemotherapy increase their risk of obesity and other illnesses, which can lead to further health issues in adulthood. Previous research shows that as little as 30 minutes of exercise in healthy kids can boost special cells in the blood called natural killer cells. Natural killer cells help to find and destroy viruses and cancer cells, and can even direct other types of cells to help.

Impact/Relevance: Showing an increase in natural killer cells after exercise in patients with ALL is the first step in understanding the role that exercise might play in boosting the immune system. By understanding the effects of exercise on the immune systems of children being treated for ALL, the study hopes to improve their health during therapy and beyond.

Funding: $14,938.75


Petros Pechlivanoglou, PhD

Project Title: Economic Evaluation of Chimeric Antigen Receptor T-cells (CART) Therapy for High-Risk Relapsed Acute Lymphoblastic Leukemia in Children

Principal Investigator: Petros Pechlivanoglou, PhD

Co-Investigators: Dr. Jason Pole, Dr. Sumit Gupta, Dr. Paul Nathan, Dr. Tal Schechter-Finkelstein, Dr. Wendy Ungar

Project Summary: Acute Lymphoblastic leukemia (ALL) is the most common childhood cancer. Although most children with ALL can be cured, those that relapse will have much lower chances to survive. Stem cell transplant (SCT) is the standard therapy for these children but is associated with high death rates and long-term complications. An alternative to SCT was developed recently: chimeric antigen receptor T-cells (CAR-T) therapy. CART therapy is very effective but also very expensive; one course of therapy costs approximately $500,000 and is currently available only in the US. We propose a study to evaluate the “value-for-money” of CART therapy compared to SCT for children with high-risk ALL who have relapsed.

Impact/Relevance: This study will provide POGO and provincial health policy makers evidence around the value-for-money of CART therapy and and so help them make better informed funding decisions.

Funding: $14,984

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June 30, 2022

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