Quick Hits 2016



Marina Salvadori, MD, FRCPC
Professor of Pediatrics
University of Western Ontario, London, ON
Pediatric Infectious Diseases Consultant
Children’s Hospital, London Health Sciences Centre , London, ON

Marina Salvadori graduated from medicine at Queen’s University in 1991. She did her residency training in pediatrics at the University of Manitoba, Winnipeg, then trained in infectious diseases at The Hospital For Sick Children in Toronto. She was working there in May 2000 and joined a team of pediatricians who responded to the call for help from Walkerton. She spent the summer of 2000 working in Walkerton, then moved to London in October 2000. She is currently an infectious diseases consultant at Children’s Hospital, London Health Sciences Centre and a Professor at the Schulich School of Medicine and Dentistry at the University of Western Ontario. She is the recipient of numerous teaching awards. She is very interested in vaccine preventable diseases, immunization education and advocacy. Dr. Salvadori is a member of the National Advisory Committee on Immunization, a past member of the Canadian Immunization and Infectious Diseases Committee.

KiCS and PROFYLE: Precision Medicine Initiatives


David Malkin, MD, FRCPC
Professor of Pediatrics and Medical Biophysics, University of Toronto
Staff Oncologist, Division of Hematology/Oncology
Senior Scientist, Genetics & Genomic Biology Program, Research Institute
The Hospital for Sick Children, Toronto, ON

Dr. Malkin is Professor of Pediatrics and Medical Biophysics, POGO Chair in Childhood Cancer Control, Faculty of Medicine, University of Toronto, and Medical Director of the Pediatric Oncology Group of Ontario. He is a pediatric oncologist, Director of the Cancer Genetics program, and a Senior Scientist in the Genetics and Genome Biology Program at SickKids. He is co-Director of the SickKids Cancer Sequencing (KiCS) program which integrates and translates next generation sequencing into clinical care of children with cancer, and Director of the national multi-institutional TFRI Precision Oncology For Young People (PROFYLE) initiative which is establishing a pipeline for incorporation of next generation sequencing and variant modeling to incorporation of novel clinical trials for children and young adults with hard to treat cancers across Canada. Dr. Malkin’s research program focuses on: 1) genetic and genomic mechanisms of childhood cancer susceptibility; and 2) signaling pathways and novel therapeutic targets in rhabdomyosarcoma. Recently, his work has addressed the application of genomics to develop rational clinical surveillance and treatment guidelines for children and adults at genetic ‘high risk’ for cancer. His work has been funded by TFRI, Canadian Cancer Society, CIHR, CFI, Genome Canada, the NIH, Ewing Foundation Canada, and the Department of Defense (US).

Minimal Residual Disease (MRD) Evaluation in Childhood ALL: A Health Policy Analysis


Nicole Bradley, MHSc
Senior Healthcare Analyst & Project Manager
Pediatric Oncology Group of Ontario (POGO)

Nicole Bradley has a Masters of Health Science (MHSc) degree in Community Health & Epidemiology from the University of Toronto. Nicole has been involved in a variety of research studies and applied analyses related to epidemiology, health services research, policy development and quality of life in pediatric and adult oncology – with 18 peer-reviewed publications and over 30 oral and poster presentations based on this work. Nicole has been awarded with numerous recognitions for her work as a young investigator, including recognition for one of the “top ten Canadian Cancer Society funded research studies of 2010.” Since 2009, Nicole has been involved with policy and program development with POGO. She is particularly interested in the use of evidence to support policy and program development and health system design to improve the quality of the healthcare system.

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