PROFYLE/KiCS: The ABCs of Precision Medicine in Canada


* Alexandra Zorzi and Anita Villani presentation slides not included 

Presentation Description:
This workshop will provide an overview of the PROFYLE (Precision Oncology for Young People) and KiCS (SickKids Cancer Sequencing) programs. Using a case-based examples, the process and associated challenges of moving patients through the precision oncology/sequencing program will be explored from the perspectives of a referring oncologist from a centre outside of Toronto, the Associate Director the KiCS program, and a Nurse Navigator who manages the practical and logistical challenges associated with care of these patients. For those with an interest in understanding how precision medicine and pediatric oncology intersect in a clinical setting, this is a must-attend session.

Alexandra Zorzi
, MD (slides unavailable)
Pediatric Oncologist
Children’s Hospital, London Health Sciences Centre

Dr. Alexandra Zorzi is a pediatric oncologist at Children’s Hospital London Health Sciences Centre and Assistant Professor at Western University. Dr. Zorzi obtained her Honours Bachelor of Science degree from the University of Toronto and her medical degree from the Schulich School of Medicine and Dentistry at Western University. She completed her pediatric residency at the University of British Columbia, and obtained her FRCPC certification in pediatrics . Her subspecialty residency in pediatric hematology/oncology was undertaken at The Hospital for Sick Children, University of Toronto.

Dr. Zorzi is currently pursuing a Master of Science degree at Western University in the Division of Physiology and Pharmacology, where she is focusing on the pharmacogenomics of chemotherapeutic agents. Her research areas of interest are chemotherapy related toxicity and developmental therapeutics.

Anita Villani, MD, MSc, FRCPC (slides unavailable)
Associate Staff Oncologist, Division of Haematology/Oncology
The Hospital for Sick Children
Assistant Professor, Department of Pediatrics
University of Toronto

Dr. Anita Villani is an Associate Staff Oncologist in the Division of Haematology/Oncology at The Hospital for Sick Children and an Assistant Professor in the Department of Pediatrics at the University of Toronto. She has a clinical and research interest in cancer genetics and predisposition, including the creation and evaluation of surveillance strategies for cancer-prone children, using both traditional and novel approaches. She has led and co-authored a number of primary research studies and guidelines on surveillance for children with cancer predisposition syndromes. Her work also aims to elucidate the unique aspects of cancer management in this patient population.

Dr. Villani is also the Associate Director of the SickKids Cancer Sequencing Program (KiCS) and focuses on the translational implementation of genomic technologies into clinical oncology care. She is interested in exploring the clinical utility of genomic findings, describing novel germline susceptibility genes and pathways, and exploring the ethics and the stakeholder experience of precision oncology research.

Dr. Villani received her medical degree from the University of Ottawa. She completed both her pediatrics residency training and hematology/oncology fellowship at The Hospital for Sick Children. She went on to obtain her Master of Science degree in Genetics and Genome Biology through the Clinician Investigator Program and Institute of Medical Science at the University of Toronto.

Andrea Cote, RN, BScN
Nurse Coordinator, New Agents and Innovative Therapies (NATI)
The Hospital for Sick Children

Andrea completed her Bachelor of Science in nursing degree at McMaster University in 2008. Upon graduation, she worked as an inpatient nurse in the Haematology/ Oncology Program at The Hospital for Sick Children. Simultaneously, she also worked as the nurse coordinator for Camp Oochigeas. She then transitioned into the nurse coordinator role for the leukemia/lymphoma team at The Hospital for Sick Children.

Most recently, Andrea developed the role of nurse coordinator within the New Agents and Innovative Therapies team at The Hospital for Sick Children. In this role Andrea coordinates patient care for children and their families from across Canada enrolled in an early phase clinical trial.

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