Osteosarcoma: Prognostic Features and New Targets

Presentation Description:  Osteosarcoma is diagnosed in 600 North Americans annually, primarily in those aged 10-30 years.  Treatment cures two-thirds with initially localized disease, 25% with initially metastatic disease.  The only other reliable prognostic feature is histologic response to induction chemotherapy.  Other biologic features may predict outcome.  Some may be therapeutic targets.


Mark L. Bernstein, MD, FRCPC
Head, Division of Hematology-Oncology, IWK Health Center; Professor of Pediatrics
Dalhousie University, Halifax, NS
Head, Division of Hematology Oncology
IWK Health Center, Halifax, NS

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