Childhood Cancer Susceptibility: Taking DNA into the Clinic

Presentation Description: With the advent of high-resolution genetic technologies, development of cancer genetics programs, and increased availability of clinical genetic testing, the practical application of genetic diagnosis of cancer susceptibility has become a reality of clinical practice. The use of genetic information in confirming diagnoses, modifying prognoses, and even providing opportunities for therapeutic intervention requires a multi-disciplinary approach to patient and family care. This presentation provided an overview of the key elements of genetic medicine that are relevant to understanding cancer susceptibility and examines the practical psychosocial and ethical implications of this ‘brave new world’ on the practice of pediatric oncology.


David Malkin, MD
Professor of Pediatrics and Medical Biophysics
University of Toronto, Toronto, ON
Staff Oncologist and Senior Scientist
The Hospital for Sick Children, Toronto, ON

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