Presentation Description: This presentation discussed cardiac complications seen in survivors of childhood cancer, including complications caused by anthracycline-associated cardiotoxicity and radiation. Approaches to cardiac late effects of cancer treatments, diagnosis and monitoring and best practices for prevention and treatment were also covered.
Ross Davies, BSc, MD, FRCPC, FACC
Member, Heart Failure, Transplant and Pulmonary Hypertension Programs
Head, Cardiology Referral Clinic, Division of Cardiology
University of Ottawa Heart Institute
Professor of Medicine
University of Ottawa
Presentation Description: This presentation focused on the clinical data that support interventions in survivor care which might impact favorably upon early detection or prevention of secondary malignancies. After a brief review of that data regarding the risks of specific types of cancers in survivors of childhood cancer and the associated risk factors for these cancers, this presentation reviewed available information that might drive clinical prevention or screening interventions. Recent advances in the understanding of oncogenesis that may define our thinking about cancer prevention in survivors were also discussed.
Lisa Diller, MD
Dana-Farber/Boston Children’s Cancer Center
Professor of Pediatrics
Harvard Medical School, Boston
Presentation Description: When a child is treated for cancer, the number of malignant cells exposed to chemotherapy and radiation is a tiny fraction of the normal cells also exposed. This unwanted exposure of normal tissues to the damaging effects of treatment is the cause of a wide array of acute and late toxicity, including infertility, cognitive impairment, and second malignancy.
This presentation described strategies to minimize the exposure of normal tissues to toxic exposures, principally radiation therapy but also chemotherapy, by advances in imaging, radiation delivery, and targeted therapeutics.
David Hodgson, MD, MPH, FRCPC
Princess Margaret Hospital, Toronto
Presentation Description: There has been a tremendous growth of interest in the concept of quality of life in recent years as awareness that medical parameters such as mortality and morbidity are not the only important outcome variables to be considered systematically. Although necessary and valuable, these outcome measures do not reflect that patient’s overall well-being and do not take into account subjective evaluation of health status and quality of life. There are several issues and challenges that have arisen in quality of life research which have generated substantial amounts of controversy and debate. These relate primarily to issues surrounding conceptualization, assessment and measurement, reflecting the lack of consensus on definition, interpretation and methods of measuring quality of life. This workshop reviewed these issues and sought to provide insight for clinicians and researchers into the investigation of quality of life.
Samantha J. Anthony, PhD, MSW, RSW
Social Worker, Transplant and Regenerative Medicine Centre
The Hospital for Sick Children, Toronto
Postdoctoral Fellow, Department of Pediatrics
McMaster University, Hamilton
Anne Klassen, BA, DPhil
Associate Professor, Department of Pediatrics
Associate Member, Department of Clinical Epidemiology & Biostatistics and
CanChild Centre for Childhood Disability Research
McMaster University, Hamilton
Adrienne D. Witol, Psy. D. R. Psych
Psychologist, Pediatric Oncology
Stollery Children’s Hospital
Assistant Professor, Department of Pediatrics
University of Alberta
Presentation Description: Although the majority of AYA survivors of childhood cancers adjust quite well, subsets of survivors may experience a number of psychological, social and/or family concerns. In addition, AYA survivors are at risk for poor adherence to survivorship follow-up treatment recommendations. These two presentations included information about general adaptation and distress, and models useful for identifying, understanding and treating AYA survivors who could benefit from psychosocial interventions.
Anne E. Kazak, PhD, ABPP
Chief, Section of Behavioural Oncology
Editor-in-Chief, Health Psychology
Director, Centre for Pediatric Traumatic Stress, The Children’s Hospital of Philadelphia
Professor, Department of Pediatrics, University of Pennsylvania, Philadelphia
Christopher J. Recklitis, PhD,l MPH
Clinical Psychologist, Dana-Farber Cancer Institute
Assistant Professor of Pediatrics, Harvard Medical School, Boston